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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a22fdd863d9dd43e96e24bfc651868d928c50aca83f9a379423e78c77f656208' 
  AND token = 'k1ZTnirmw02PZMd4iT1MlKYj3IeB2X10INcG5OmG17I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}