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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5381e0069584e48d9a5fe12e92e9c0fe10f3d8b29bee85431c6004fa6b1fadc4' 
  AND token = '2ptOgsKhfTs+YbpOeY0SgkRL9PUlcf0iMdewG07UqGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}