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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '807ef7ba69baad30d3ed7a00e44e04f4a3b80afecfc59ba327ab9b76e5c42224' 
  AND token = '+Lokx7wTdaUBVdY5WDSazhv7A/va6FTrCcD9xim+Mu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}