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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1f58d27b95e81343164d7c586d27f77f34aa9d378d9242f030dd63ce652ee87' 
  AND token = 'XlLj+y+i1GRzinFMX/OKtOU3NkOagUaJarQPctNAyeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}