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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4de9877e23809891656468b33135c2fa7914f94b6af70666742f452f3b48cd20' 
  AND token = 'Mv8JP866CsQMpNaGE6vUioGM/qttHiuRiMRhvV3wUIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}