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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e81bee601e6cea3b513efe68995ffd3d0cb51ae73ecf62ac07fde958251362' 
  AND token = 'R/38jIHhp9/D5SA5+pVmPbOyx8hw2ooRcORbav017i4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}