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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f379225822326819bc1a13d6178443e966d70ea35ab44409e1c9abd33a270f6' 
  AND token = '+/WXlQleQ4ckEsMimEUJyOZXQx8tS58SOiOA9qk3SzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00068

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}