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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cf7c3fe00c182efd504e634ac1fe5f860165fefe58c59252fe7a16a9f2ce0ee' 
  AND token = '+kP5tQ/GjYnxWUXAkXUSmWQAp9r9dv0xLvD9V0Ltc20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}