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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97b208b2d869c828ff27bddd06c7989192b795cca318ba90e4528c6433054d0a' 
  AND token = '4/P+4NTQKG8+yQqVeQ37yXzXQmAKRGG91lQWgwNoyk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}