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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e18b737dad9be08125684a5c167e269da33a9acf4309c4c0e32bd68d13beaf9b' 
  AND token = 'yplSngjJnYShMm9hbqjo51aDf8hXhn6X+9pri/e6ZH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}