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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aace801fbb15835bacaa1475d90b0155e0d1f4994652af0cb106ba11e078be47' 
  AND token = '9qenmMIPZBw+4pL/mRgaWL5jlZqSLZHnTe5SKT4n6co=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00070

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}