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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e78ec09ce64e9a248fd0000242d645d8970a023be588e291dc8731fe24033cd' 
  AND token = 'y+1ujVd2lsgJs6nCGN4MtXAGBCGHxKpW80YfUjSkFu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}