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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7346ecd680cf65cda5d4f40b10114207df2075c34c5b95f9a2901dd4b9eab2cf' 
  AND token = 'eDkyBQUPj2GX6ANFk1WinMjGr5gMkA2aY+dUKa8a8hA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}