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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6aafba9e5d37d117f75a1a83f578ac7e2246e56747ec4e746897d5151fab2001' 
  AND token = 'pqgUdAvWDCWsbQKK7uNKB/x9IXXQ6+RzyxfZD4uLtfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}