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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f8a87a0d5431a3e1005aa6804e4ff1a1d91868ccbc1e0450fbd272dad13f59d' 
  AND token = 'ERiiG5CoRXpPqE+Vi3qBm86Nh2i9u8rwcVRhRniye/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}