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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45d9efeeb4e728fb83dcd71f795d371d47980014c16ee68c8651d87055e51287' 
  AND token = '8i1wGvGjbbCn+HLn/5pyAi02OoxnxraurTaYZUqmvcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}