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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f035baf54a3ba4cd46883a729202418a69765c6f43d99b608a2d44b99c0b607d' 
  AND token = '7N4iPz48dlmQsLDv3tJotmpTsodG7IygMbWyuU8XD6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}