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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45f1d6e5310f589613baeaaea84b14bae029e7fb131bdb076a11cc16cbd6aa8b' 
  AND token = '2tFj7043/+WyH9gKkwlwFQUvlwbDcdfB0XGB0UPj8h8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}