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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '246ca7384d354fbac1f787f3d1253215a6d4cf8f23f04939f6e325ee56fac56c' 
  AND token = 'rDiZXN+EPrLFLUig6w4AABZBSyUq45elGyWM7pMg2eg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}