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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c850d6e01c0b24d71edf21b9c2480cd1d482f942132c801f01e9b4d48fa5443b' 
  AND token = 'ikTJGDqddRvC1bZxc0DtLsI5f2ZXuTPj7NHjzjtxJp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}