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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eaf7260425504a787ed467add891018498e40c5dab00c5bbd0639e0a4d20727' 
  AND token = 'xS8bOc5uImy+dZogt1uDjZwGOj7O9IZzO8/X8uRk2gM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}