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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f382cce8cc0fabc92f6c9e9e5aa8d80a0bc564d2210c07d0d2fedbaa51d2102' 
  AND token = 'DEmtf1RDlaYg0aRSDozGWG+5zd/HBcutp1SKzOZ50TY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}