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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd659c08aa04a53298fe12880951f4f6085ed138332d6c19631f9cb65b2a4453' 
  AND token = 'KGV8n61ZYtRnBoW7E9isVfwa6DDU2va4wnCWmK0pLEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}