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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ad854b6225668d68fe8ff6b64a2bcf00ff83527a48d2e62bb9e11af473a6a18' 
  AND token = '9/cud0pQrBPedFOSZ+tp7aL2qB1nxTVFSPLElCeqmwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}