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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1897416ab03bce03fcdfb66a3084cd7700dfca731b5eac3e3b66e3c9e0ec3177' 
  AND token = 'ZtHkKvhS4mdGwiexbtqSNRQHrywywvNWJUyS0OpjqE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}