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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39b29b7c22a9ba5dada0dc555ad7da0e1a6b04934c74189dacbf759d48ef3545' 
  AND token = 'OnNz9dXUY0SLW5Hq/Wa1aG6uam3e7pBEuBMJST3SGhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}