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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2890815dca9cf2eae8ad70c3aca60bd2e273011706739ef3da3c1ee5a0fedf96' 
  AND token = '66FVkiYzh7XrMkBcfYfohpdRX5Hr/YFV+39GWvgJ6Tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}