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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e123a591dc8321bfdcca8a0c3994d2bac6b1fa4b4886b9683e41cc702030afc' 
  AND token = 'ddhyIEPnwBJqoi2t72VnYAWzA/kPAkbITkDygy2OmsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}