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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52715ce869954cb8a08042e2d7e71e5b8833fd45a8ef79b8f3eaac689e496478' 
  AND token = 'zVBaZdNDmvHPLtbe0FPPexLJHjlrfTNd2ne8qtAoTHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}