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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6ed65dbf218cd2fa57517998c722b52cb0fca2a9e6d3de1b4289ed73866f321' 
  AND token = 'aQc3qvWSHZLRngYsMOBW08iK3xs1cvZKAjgKsfx6wmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}