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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ed7173d722f200d2c4128855947177acbc96d6d6949b32349bb1ab159960987' 
  AND token = 'UfIL7JSbkwmGVH07bV7TaX27KfzrTTj1HSNqUZ+jgXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}