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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b679ced105c4a82a846484f72e5c2f03f2521f8811f917fbf0471e289b61424' 
  AND token = 'Z1OQ7rGXnIPlxjNxa3Y+2sDYGGmtEGa9AysK1yT305A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}