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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca086a9c583b4c2479ad41dac192125ce25abf07bd3dd2cb1982f1ab24f1588a' 
  AND token = 'OfsT+jGGrWXyBYbJeXf/dSmEEGY05me3MJsaRjge5Wg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}