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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd68b1b3c2c3155f99fd4462a2fe4d0245da2264a45084d7e44ced3a30298032e' 
  AND token = 'DZtMeKON5LRbYMdejXEDFl1kgFfvuNpKJ3XUmVozBiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}