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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc4fb43bd1a7534a7f42420331a3ed303c05d03b8977b5d17d29aa448bb68c60' 
  AND token = 'xKzCyaUGWz7T/DZItRPOCd0lzvVMWybyba/WOuFOA00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}