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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78137d6156ad46af16025a931a5c8cfddeb659bdd757a2eb6c8ef3a581fc4970' 
  AND token = '5IlvaUHS+9w+RjPUjM/dfkMBsup06JaqCXFuUCa3S1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}