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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8376f3992319971e9ad3d3cf0d702e56b790cc4b0c906bb37d634d2803149331' 
  AND token = '+u7XAR6UxjGMDEE0RjAcycIYBnHvCGTmMa88jz9Tv/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}