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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1d35523f5ce282eef8563c39a49cbacb4443917b0d30d3b4c47e641b9ef0950' 
  AND token = 'UgxKd+2S0BM8F9Im/nud24jQ5Z7c2Gt7QoT150k+AkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}