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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10da6c93d6ba982d40ee292caabeb2e4e0bd4782243a2a7e239fbd67730a5e05' 
  AND token = 'yvv2+DNK5T26iPKf6L9jzHRQ3ps/rD9BCkVfVHWXrBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}