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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab528c67d8b5e9e36be7cf20613ffc293f447f32d437ee5cc918ffb0da15ff65' 
  AND token = '+XDk88Y50013fE7TphLNQjmr//DgNZNzxyWSBQ4e7r8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}