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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b20d5b8ba1e8e5692718b4ca3396454fa2b246b071c525e301939bc5d2ff063' 
  AND token = 'wdLfPWHee4RkbtBupmsoQfx85ui4qb4FCWCx+XTevvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}