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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ee0227ca5fe3878c803cbe42bbbf38cef62067b9a5eb71469a4133e320a9764' 
  AND token = 'WVd3hxfa1SoX8ACVXKKZqyhtTVXQcW8WHiugAnovN/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}