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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a52ad74b108278b1579d99a1598b85c2ffd9f2d9e887ad0171e7378c51192c0d' 
  AND token = '8vhpyilenYDqvP5a6CCD1isVyvScejID6s8ShHHfOVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}