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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9688b285b75d9edeb67bbc8ff783c42d784383cb83926ea70947db95b840f369' 
  AND token = 'H+z4x7vnIamMYD1+C/tSr3C8U+uPkqY2OIS0bbHqJ0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}