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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c759bdd8cadfd05afeb1a80183559672d8614ea4f82570549d3eb1f714e58ea' 
  AND token = 'qwtlxh+7P7t0/omemyiw0t+1no3p7I3nn+Z/+SARHkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}