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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '270f2bfcdc97ba073125d4b1c550ac16195c10ad37ffafd9b87ec4ae6787645e' 
  AND token = 'JYED2djM2sZvzvi3Lyd+37TCaU+5KS2dsZUI5j/CWIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}