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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c86f574e00af35e305c756988a3a62dc556fdf4e2f2d7b0d143fe43ba155834' 
  AND token = 'u27BuNJ6CvMtZmLoGNASAIi3W/tHeDmwpiwYtjcjnYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}