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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6417378534d03d464301f3f31e1b276749182607228c226afd8bfdd6a6f010f' 
  AND token = 'kBo2SJvuy8VD4q35RRAc693X7g6qWCUKTdoLlA39Q7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}