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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f3f9f4aef988df8663ad9962168a15df12c0d0011e710377fadd4735e0bfd9f' 
  AND token = 'hQqQjNtP3LdbP+icZdOPynfqz73UV/H4hYLentuXFls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}