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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e046194d3dbccd1977a197281c9d46a7d8e24470263d31993714d6fa17024ad' 
  AND token = 'XH0Ki8Zuyk2cB9z3eZsyP6NWu1hwv0DEyPd8AKcL5Gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}